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Pby1 is a direct partner of the Dcp2 decapping enzyme

Archive ouverte | Charenton, Clément | CCSD

International audience. Most eukaryotic mRNAs harbor a characteristic 5 m 7 GpppN cap that promotes pre-mRNA splicing, mRNA nucleocytoplasmic transport and translation while also protecting mRNAs from exonucleolytic...

A unique surface on Pat1 C-terminal domain directly interacts with Dcp2 decapping enzyme and Xrn1 5′–3′ mRNA exonuclease in yeast

Archive ouverte | Charenton, Clément | CCSD

International audience. The Pat1 protein is a central player of eukaryotic mRNA decay that has also been implicated in translational control. It is commonly considered a central platform responsible for the recruitm...

Recruitment of the mRNA decay machineries to the 5’ end of mRNAs

Archive ouverte | Charenton, Clément | CCSD

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