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In Vitro Screening of a 1280 FDA-Approved Drugs Library against Multidrug-Resistant and Extensively Drug-Resistant Bacteria

Archive ouverte | Peyclit, Lucie | CCSD

International audience. Alternative strategies against multidrug-resistant (MDR) bacterial infections are suggested to clinicians, such as drug repurposing, which uses rapidly available and marketed drugs. We gather...

Drug Repurposing to Fight Colistin and Carbapenem-Resistant Bacteria

Archive ouverte | Peyclit, Lucie | CCSD

International audience. The emergence of new resistance mechanisms, the failure of classical antibiotics in clinic, the decrease in the development of antibiotics in the industry are all challenges that lead us to c...

Inactivation of thymidine kinase as a cause of resistance to zidovudine in clinical isolates of Escherichia coli: a phenotypic and genomic study

Archive ouverte | Peyclit, Lucie | CCSD

International audience. Objectives: The antiviral zidovudine has been recently identified as an active drug against resistant Enterobacteriaceae, but prevalence of resistance to this compound remains unknown. The ai...

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