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Risk of Intracranial Aneurysm and Dissection and Fluoroquinolone Use: A Case-Time-Control Study. : Stroke

Archive ouverte | Maumus-Robert, Sandy | CCSD

International audience. Background and Purpose—Fluoroquinolone use is associated with an increased risk of aortic aneurysm and dissection. We investigated this risk of arterial wall injury on intracranial arteries, ...

Primary Care of Opioid use Disorder: The End of "the French Model"?. : Eur Addict Res

Archive ouverte | Dupouy, J. | CCSD

International audience. Background: In France, most patients with opioid use disorder (OUD) have been treated by buprenorphine, prescribed by general practitioners (GP) in private practice since 1996. This has contr...

Propensity Score-Based Approaches in High Dimension for Pharmacovigilance Signal Detection: an Empirical Comparison on the French spontaneous Reporting Database

Archive ouverte | Courtois, E. | CCSD

International audience. Classical methods used for signal detection in pharmacovigilance rely on disproportionality analysis of counts aggregating spontaneous reports of a given adverse drug reaction. In recent year...

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