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Diacylated sulfoglycolipids are novel mycobacterial antigens stimulating CD1-restricted T cells during infection with Mycobacterium tuberculosis.

Archive ouverte | Gilleron, Martine | CCSD

Mycobacterial lipids comprise a heterogeneous group of molecules capable of inducing T cell responses in humans. To identify novel antigenic lipids and increase our understanding of lipid-mediated immune responses, we established ...

Cutting edge: a naturally occurring mutation in CD1e impairs lipid antigen presentation.

Archive ouverte | Tourne, Sylvie | CCSD

International audience. The human CD1a-d proteins are plasma membrane molecules involved in the presentation of lipid Ags to T cells. In contrast, CD1e is an intracellular protein present in a soluble form in late e...

Cutting edge: a naturally occurring mutation in CD1e impairs lipid antigen presentation

Archive ouverte | Tourne, Sylvie | CCSD

UMRS1255. International audience. The human CD1a-d proteins are plasma membrane molecules involved in the presentation of lipid Ags to T cells. In contrast, CD1e is an intracellular protein present in a soluble form...

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