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A photoswitchable GABA receptor channel blocker

Archive ouverte | Maleeva, Galyna | CCSD

International audience. Background and Purpose Anion-selective Cys-loop receptors (GABA and glycine receptors) provide the main inhibitory drive in the CNS. Both types of receptor operate via chloride-selective ion ...

Action of the Photochrome Glyght on GABAergic Synaptic Transmission in Mouse Brain Slices

Archive ouverte | Petukhova, Elena | CCSD

International audience. Glyght is a new photochromic compound described as an effective modulator of glycine receptors at heterologous expression, in brain slices and in zebrafish larvae. Glyght also caused weak inh...

Voltage-Dependent Inhibition of Glycine Receptor Channels by Niflumic Acid

Archive ouverte | Maleeva, Galyna | CCSD

International audience. Niflumic acid (NFA) is a member of the fenamate class of nonsteroidal anti-inflammatory drugs. This compound and its derivatives are used worldwide clinically for the relief of chronic and ac...

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