Syracuse

In vitro/in vivo evidences of the efficacy of novel amphiphilic derivatives of PEG for producing long-circulating lipid-based nanocarriers

Archive ouverte | Basile, L. | CCSD

Serum-stable, long-circulating paclitaxel-loaded colloidal carriers decorated with a new amphiphilic PEG derivative

Archive ouverte | Basile, L. | CCSD

International audience. The paper describes sterically stabilized lipid nanocapsules (LNC) and multilamellar liposomes (MLV) coated using a new amphiphilic conjugate of PEG2000 with a 2-alkyl-lipoamino acid (LAA). A...

Brain Tumors: Convection-Enhanced Delivery of Drugs (Method)

Archive ouverte | Lainé, Anne-Laure | CCSD

Delivery of therapeutic agents into the brain has been an ongoing challenge for many years. The poor prognosis for patient with primary malignant brain tumors treated with conventional techniques (surgery, radiotherapy and chemoth...