L-Arginine Improves Endurance to High-Intensity Interval Exercises in Overweight Men

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Daraei, Ali | Ahmadizad, Sajad | Rahmani, Hiwa | Hackney, Anthony C. | Johnson, Kelly E. | Laher, Ismail | Saeidi, Ayoub | Zouhal, Hassane

Edité par CCSD ; Human Kinetics -

International audience. The effects of acute consumption of L-Arginine (L-Arg) in healthy young individuals are not clearly defined, and no studies on the effects of L-Arg in individuals with abnormal body mass index undertaking strenuous exercise exist. Thus, we examined whether supplementation with L-Arg diminishes cardiopulmonary exercise testing responses, such as ventilation (VE), VE/VCO2, oxygen uptake (VO2), and heart rate, in response to an acute session of high-intensity interval exercise (HIIE) in overweight men. A double-blind, randomized crossover design was used to study 30 overweight men (age, 26.5 +/- 2.2 years; body weight, 88.2 +/- 5.3 kilogram; body mass index, 28.0 +/- 1.4 kg/m(2)). Participants first completed a ramped-treadmill exercise protocol to determine VO(2)max velocity (vVO(2)max), after which they pAarticipated in two sessions of HIIE. Participants were randomly assigned to receive either 6 g of L-Arg or placebo supplements. The HIIE treadmill running protocol consisted of 12 trials, including exercise at 100% of vVO(2)max for 1 min interspersed with recovery intervals of 40% of vVO(2)max for 2 min. Measurements of VO2 (ml.kg(-1) .min(-1)), VE (L/min), heart rate (beat per min), and VE/VCO2 were obtained. Supplementation with L-Arg significantly decreased all cardiorespiratory responses during HIIE (placebo+HIIE vs. L-Arg+HIIE for each measurement: VE [80.9 +/- 4.3 L/min vs. 74.6 +/- 3.5 L/min, p <.05, ES = 1.61], VE/VCO2 [26.4 +/- 1.3 vs. 24.4 +/- 1.0, p <.05, ES = 1.8], VO2 [26.4 +/- 0.8 ml.kg(-1).min(-1) vs. 24.4 +/- 0.9 ml.kg(-1).min(-1), p <.05, ES = 2.2], and heart rate [159.7 +/- 6.3 beats/min vs. 155.0 +/- 3.7 beats/min, p <.05, d = 0.89]). The authors conclude consuming L-Arg before HIIE can alleviate the excessive physiological strain resulting from HIIE and help to increase exercise tolerance in participants with a higher body mass index who may need to exercise on a regular basis for extended periods to improve their health.

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