EURADOS REVIEW OF RETROSPECTIVE DOSIMETRY TECHNIQUES FOR INTERNAL EXPOSURES TOIONISING RADIATION AND THEIR APPLICATIONS

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Giussani, Augusto | Lopez, Maria Antonia | Romm, Horst | Testa, Antonella | Ainsbury, Elisabeth | Degteva, Marina | Della Monaca, Sara | Etherington, George | Fattibene, Paola | Guclu, Inci | Jaworska, Alicja | Lloyd, David | Malatova, Irena | Mccomish, Stacey | Melo, Dunstana | Osko, Jakub | Rojo, Ana | Roch-Lefevre, Sandrine | Roy, Laurence | Shishkina, Elena | Sotnik, Natalia | Tolmachev, Sergey | Wieser, A. | Woda, Clemens | Youngman, Mike

Edité par CCSD ; Springer Verlag -

International audience. This work presents an overview of the applications of retrospective dosimetry techniques in case ofincorporation of radionuclides. The fact that internal exposures are characterized by a spatiallyinhomogeneous irradiation of the body, which is potentially prolonged over large periods andvariable over time, is particularly problematic for biological and electron paramagnetic resonance(EPR) dosimetry methods when compared to external exposures.The paper gives initially specific information about internal dosimetry methods, the most commoncytogenetic techniques used in biological dosimetry and EPR dosimetry applied to tooth enamel.Based on real case scenarios, dose estimates obtained from bioassay data as well as with biologicaland/or EPR dosimetry are compared and critically discussed.In most of the scenarios presented, concomitant external exposures were responsible for the greaterportion of the received dose. As no assay is available which can discriminate between radiation ofdifferent types and different LETs on the basis of the type of damage induced, it is not possible toinfer from these studies specific conclusions valid for incorporated radionuclides alone. The biologicaldosimetry assays and EPR techniques proved to be most applicable in cases when the radionuclidesare almost homogeneously distributed in the body. No compelling evidence was obtained in othercases of extremely inhomogeneous distribution. Retrospective dosimetry needs to be optimized andfurther developed in order to be able to deal with real exposure cases, where a mixture of bothexternal and internal exposures will be encountered most of the times.

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