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The functional convergence of antibiotic resistance in β‐lactamases is not conferred by a simple convergent substitution of amino acid

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Keshri, Vivek | Arbuckle, Kevin | Chabrol, Olivier | Rolain, Jean‐marc | Raoult, Didier | Pontarotti, Pierre

Edité par CCSD ; Blackwell -

International audience. Antibiotics are medicines that fight bacterial infection, but there is a growing problem of antibiotic resistance when bacteria become able to resist the effects of antibiotics. Antibiotic-resistant genes spread in the environment quickly due to overuse of antibiotics which imposes a strong selection pressure favoring resistance. For instance, humans use a range of antibiotics in agriculture and fish farming, as standard prophylactic measures, which leads to the widespread evolution of antibiotic-resistant genes (Economou & Gousia, 2015). A common enzymatic resistance

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