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Removing Critical Gaps in Chemical Test Methods by Developing New Assays for the Identification of Thyroid Hormone System-Disrupting Chemicals—The ATHENA Project

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Kortenkamp, Andreas | Axelstad, Marta | Baig, Asma | Bergman, Åke | Bornehag, Carl-Gustaf | Cenijn, Peter | Christiansen, Sofie | Demeneix, Barbara | Derakhshan, Arash | Fini, Jean-Baptiste | Frädrich, Caroline | Hamers, Timo | Hellwig, Lina | Köhrle, Josef | Korevaar, Tim I.M. | Lindberg, Johan | Martin, Olwenn | Meima, Marcel | Mergenthaler, Philipp | Nikolov, Nikolai | Du Pasquier, David | Peeters, Robin | Platzack, Bjorn | Ramhøj, Louise | Remaud, Sylvie | Renko, Kostja | Scholze, Martin | Stachelscheid, Harald | Svingen, Terje | Wagenaars, Fabian | Wedebye, Eva Bay | Zoeller, R. Thomas

Edité par CCSD ; MDPI -

International audience. The test methods that currently exist for the identification of thyroid hormone system-disrupting chemicals are woefully inadequate. There are currently no internationally validated in vitro assays, and test methods that can capture the consequences of diminished or enhanced thyroid hormone action on the developing brain are missing entirely. These gaps put the public

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