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microRNA-mediated regulation of mTOR complex components facilitates discrimination between activation and anergy in CD4 T cells.

Archive ouverte | Marçais, Antoine | CCSD

International audience. T cell receptor (TCR) signals can elicit full activation with acquisition of effector functions or a state of anergy. Here, we ask whether microRNAs affect the interpretation of TCR signaling...

The role of the Xist 5' m6A region and RBM15 in X chromosome inactivation

Archive ouverte | Coker, Heather | CCSD

International audience. Background: X chromosome inactivation in mammals is regulated by the non-coding (nc) RNA, Xist, which represses the chromosome from which it is transcribed.  High levels of the N6-methyladeno...

Cross-talking noncoding RNAs contribute to cell-specific neurodegeneration in SCA7

Archive ouverte | Tan, Jennifer | CCSD

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