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Implication of Heat Shock Factors in Tumorigenesis: Therapeutical Potential

Archive ouverte | de Thonel, Aurélie | CCSD

International audience. Heat Shock Factors (HSF) form a family of transcription factors (four in mammals) which were named according to the discovery of their activation by a heat shock. HSFs trigger the expression ...

Transcriptional regulation of small HSP—HSF1 and beyond

Archive ouverte | de Thonel, Aurélie | CCSD

International audience. The members of the small heat shock protein (sHSP) family are molecular chaperones that play major roles in development, stress responses, and diseases, and have been envisioned as targets fo...

The “HSF connection”: Pleiotropic regulation and activities of Heat Shock Factors shape pathophysiological brain development

Archive ouverte | Duchateau, Agathe | CCSD

International audience. The Heat Shock Factors (HSFs) have been historically identified as a family of transcription factors that are activated and work in a stress-responsive manner, after exposure to a large varie...

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