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Tubulin polyglutamylation is a general traffic-control mechanism in hippocampal neurons

Archive ouverte | Bodakuntla, Satish | CCSD

International audience. Neurons are highly complex cells that heavily rely on intracellular transport to distribute a range of functionally essential cargoes within the cell. Post-translational modifications of tubu...

Evidence for new C-terminally truncated variants of - and -tubulins

Archive ouverte | Aillaud, Chrystelle | CCSD

International audience. Cellular α-tubulin can bear various carboxy-terminal sequences: full-length tubulin arising from gene neosynthesis is tyrosinated, and two truncated variants, corresponding to detyrosinated a...

Cell-Intrinsic Control of Interneuron Migration Drives Cortical Morphogenesis

Archive ouverte | Silva, Carla | CCSD

International audience. Graphical Abstract Highlights d CCP1 controls MLCK activity by processing its polyglutamate carboxy-terminal d CCP1 controls the stereotypic two-stroke cycle of cortical interneuron migration...

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