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Remodeling of heparan sulfate : functional and structural characterization of human endosulfatase HSulf-2. Remodelage des heparanes sulfate : caractérisation fonctionnelle et structurale de l'endosulfatase humaine HSulf-2

Archive ouverte | El Masri, Rana | CCSD

Heparan Sulfate (HS) are complex polysaccharides involved in many biological processes. The structure of HS is regulated at the cell surface by unique extracellular endosulfatases, the Sulfs. Sulfs dramatically change HS functiona...

HS and Inflammation: A Potential Playground for the Sulfs?

Archive ouverte | El Masri, Rana | CCSD

International audience. Heparan sulfate (HS) is a complex polysaccharide abundantly found in extracellular matrices and cell surfaces. HS participates in major cellular processes, through its ability to bind and mod...

The "in and out" of glucosamine 6-O-sulfation: the 6th sense of heparan sulfate.

Archive ouverte | El Masri, Rana | CCSD

International audience. The biological properties of Heparan sulfate (HS) polysaccharides essentially rely on their ability to bind and modulate a multitude of protein ligands. These interactions involve internal ol...

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