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Apoptosis in Drosophila: which role for mitochondria?

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International audience. It is now well established that the mitochon-drion is a central regulator of mammalian cell apoptosis. However, the importance of this organelle in non-mam-malian apoptosis has long been rega...

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International audience. The ubiquitin-proteasome system is one of the main proteolytic pathways. It inhibits apoptosis by degrading pro-apoptotic regulators, such as caspases or the tumor suppressor p53. However, it...

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International audience. The tumor suppressor retinoblastoma protein (pRb) is inactivated in a wide variety of cancers. While its role during cell cycle is well characterized, little is known about its properties on ...

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