Afficher la couverture 'A chicken liver cell line efficiently supports the replication of ALV-J possibly through its high level viral receptor and efficient protein expression system | Li, Tuofan' en grand format
/5

0 avis

A chicken liver cell line efficiently supports the replication of ALV-J possibly through its high level viral receptor and efficient protein expression system

Archive ouverte

Li, Tuofan | Xie, Jing | Lv, Lu | Sun, Shu | Dong, Xiaomei | Xie, Quan | Liang, Guangcheng | Xia, Chichao | Shao, Hongxia | Qin, Aijian | Ye, Jianqiang

Edité par CCSD ; BioMed Central -

International audience. AbstractIn this study, we identified a chicken liver cell line (LMH) which could strongly support the replication of ALV-J (Subgroup J of avian leukosis virus) with high viral titer. Notably, ALV-J was efficiently detected by ELISA in LMH cells 1 day before DF1 cells. In comparison with DF1 cells, LMH cells not only expressed higher levels of ALV-J receptor chNHE-1, but also possessed a more efficient protein expression system for foreign genes. Thus, LMH cells could be a novel tool to shorten the ALV-J eradication approach and accelerate studies on the pathogenesis and oncogenesis of ALV-J.

Suggestions

Du même auteur

A novel fiber-2-edited live attenuated vaccine candidate against the highly pathogenic serotype 4 fowl adenovirus

Archive ouverte | Xie, Quan | CCSD

International audience. Recently, the outbreaks of hydropericardium-hepatitis syndrome (HHS) caused by the highly pathogenic fowl adenovirus serotype 4 (FAdV-4) have resulted in huge economic losses to the poultry i...

A novel monoclonal antibody efficiently blocks the infection of serotype 4 fowl adenovirus by targeting fiber-2

Archive ouverte | Wang, Ping | CCSD

International audience. AbstractA recent outbreak of hepatitis–hydropericardium syndrome caused by serotype 4 fowl adenovirus (FAdV-4) has resulted in significant economic losses to the poultry industry worldwide. H...

A novel CAV derived cell-penetrating peptide efficiently delivers exogenous molecules through caveolae-mediated endocytosis

Archive ouverte | Hu, Gaowei | CCSD

International audience. AbstractCell-penetrating peptide (CPP) is a promising cargo for delivering bioactive molecules. In this study, the N terminus of VP1 from chicken anemia virus, designated as CVP1, was found t...

Chargement des enrichissements...