Excito-repellency and biological safety of β-caryophyllene oxide against Aedes albopictus and Anopheles dirus (Diptera: Culicidae)

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Nararak, Jirod | Di Giorgio, Carole | Sukkanon, Chutipong | Mahiou-Leddet, Valerie | Ollivier, Evelyne | Manguin, Sylvie | Chareonviriyaphap, Theeraphap

Edité par CCSD ; Elsevier -

International audience.  β-caryophyllene oxide had stronger repellent and irritant effect than DEET  Ae. albopictus was more sensitive to β-caryophyllene oxide than An. dirus while, knockdown responses (37%) were observed in An. dirus exposed to 1% β-caryophyllene oxide in the contact trial.  β-caryophyllene oxide did not show any phototoxic activity.  None of the tested β-caryophyllene oxide induced a significant increase of micronucleated cells with or without metabolic activation.  β-Caryophyllene oxide could be considered as a safe repellent, effective against mosquitoes.

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