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Epigenome and transcriptome landscapes highlight dual roles of proinflammatory players in a perinatal model of white matter injury

Archive ouverte | Schang, Anne--Laure | CCSD

Premature birth is the commonest cause of death and disability in young children. Diffuse white matter injury (DWMI), provoked by inflammatory insults accompanying prematurity, is associated with increased risk of neurodevelopment...

Bisphenol A exposure during gestation and lactation in mice: Sex-specific consequences on oligodendrocytes and myelination

Archive ouverte | Naffaa, Vanessa | CCSD

International audience. Bisphenol A (BPA), a ubiquitous environmental endocrine disruptor, is suspected of disturbing brain development through largely unknown cellular and molecular mechanisms. In the central nervo...

Epigenetic priming of immune/inflammatory pathways activation and abnormal activity of cell cycle pathway in a perinatal model of white matter injury

Archive ouverte | Schang, Anne-Laure | CCSD

International audience. Abstract Prenatal inflammatory insults accompany prematurity and provoke diffuse white matter injury (DWMI), which is associated with increased risk of neurodevelopmental pathologies, includi...

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