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Natural killer cell infiltration is discriminative for antibody-mediated rejection and predicts outcome after kidney transplantation

Archive ouverte | Yazdani, Saleh | CCSD

International audience. Despite partial elucidation of the pathophysiology of antibody-mediated rejection (ABMR) after kidney transplantation, it remains largely unclear which of the involved immune cell types deter...

Development and validation of a peripheral blood mRNA assay for the assessment of antibody-mediated kidney allograft rejection: A multicentre, prospective study

Archive ouverte | van Loon, Elisabet | CCSD

International audience. BackgroundAntibody-mediated rejection, a leading cause of renal allograft graft failure, is diagnosed by histological assessment of invasive allograft biopsies. Accurate non-invasive biomarke...

Biological pathways and comparison with biopsy signals and cellular origin of peripheral blood transcriptomic profiles during kidney allograft pathology

Archive ouverte | van Loon, Elisabet | CCSD

International audience. Kidney transplant injury processes are associated with molecular changes in kidney tissue, primarily related to immune cell activation and infiltration. How these processes are reflected in t...

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