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The Ubiquitin Ligase Rsp5p is Required for the Modification and Sorting of Biosynthetic Membrane Proteins into Multivesicular Bodies in S. cerevisiae.

Archive ouverte | Morvan, Joelle | CCSD

Precursor forms of vacuolar proteins with transmembrane domains, such as the carboxypeptidase S Cps1p and the polyphosphatase Phm5p, are selectively sorted in endosomal compartments to vesicles that invaginate, budding into the lu...

The ubiquitin ligase Rsp5p is required for modification and sorting of membrane proteins into multivesicular bodies

Archive ouverte | Morvan, Joelle | CCSD

International audience. Precursor forms of vacuolar proteins with transmem-brane domains, such as the carboxypeptidase S Cps1pand the polyphosphatase Phm5p, are selectively sortedin endosomal compartments to vesicle...

Antagonistic roles of ESCRT and Vps Class C/HOPS complexes in the recycling of yeast membrane proteins

Archive ouverte | Bugnicourt, Amandine | CCSD

International audience. In Saccharomyces cerevisiae, deficiencies in the ESCRT machinery trigger the mistargeting of endocytic and biosynthetic ubiquitinated cargoes to the limiting membrane of the vacuole. Surprisi...

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