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Robustness and power of single-SNP analysis in related populations

Archive ouverte | Teyssedre, Simon, S. | CCSD

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Statistical distributions of test statistics used for quantitative trait association mapping in structured populations

Archive ouverte | Teyssedre, Simon, S. | CCSD

Background: Spurious associations between single nucleotide polymorphisms and phenotypes are a major issue in genome-wide association studies and have led to underestimation of type 1 error rate and overestimation of the number of...

Genome-wide association studies for osteochondrosis in French trotter horses

Archive ouverte | Teyssèdre, Simon, S. | CCSD

A genome-wide association study for osteochondrosis (OC) in French Trotter horses was carried out to detect QTL using genotype data from the Illumina EquineSNP50 BeadChip assay. Analysis data came from 161 sire families of French ...

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