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Transcriptome analysis of Wnt3a-treated triple-negative breast cancer cells

Archive ouverte | Maubant, Sylvie | CCSD

International audience. The canonical Wnt/beta-catenin pathway is activated in triple-negative breast cancer (TNBC). The activation of this pathway leads to the expression of specific target genes depending on the c...

TTK/hMPS1 is an attractive therapeutic target for triple-negative breast cancer

Archive ouverte | Maire, Virginie | CCSD

Triple-negative breast cancer (TNBC) represents a subgroup of breast cancers (BC) associated with the most aggressive clinical behavior. No targeted therapy is currently available for the treatment of patients with TNBC. In order ...

Polo-like Kinase 1: A Potential Therapeutic Option in Combination with Conventional Chemotherapy for the Management of Patients with Triple-Negative Breast Cancer

Archive ouverte | Maire, Virginie | CCSD

Breast cancers are composed of molecularly distinct subtypes with different clinical outcomes and responses to therapy. To discover potential therapeutic targets for the poor prognosis-associated triple-negative breast cancer (TNB...

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