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Transcriptomic analyses reveal rhythmic and CLOCK-driven pathways in human skeletal muscle

Archive ouverte | Perrin, Laurent | CCSD

International audience. Circadian regulation of transcriptional processes has a broad impact on cell metabolism. Here, we compared the diurnal transcriptome of human skeletal muscle conducted on serial muscle biopsi...

Lipidomics reveals diurnal lipid oscillations in human skeletal muscle persisting in cellular myotubes cultured in vitro

Archive ouverte | Loizides-Mangold, Ursula | CCSD

International audience. Circadian clocks play an important role in lipid homeostasis, with impact on various metabolic diseases. Due to the central role of skeletal muscle in whole-body metabolism, we aimed at study...

Alterations of lipid homeostasis in morbid obese patients are partly reversed by bariatric surgery

Archive ouverte | Sinturel, Flore | CCSD

International audience. HighlightsGBS results in phosphoand sphingolipid rearrangement in morbid obese patients GBS impacts differentially the lipid metabolism in serum and SAT GBS partly restores the lipid landscap...

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