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Two members of the beige/CHS (BEACH) family are involved at different stages in the organization of the endocytic pathway in Dictyostelium

Archive ouverte | Cornillon, Sophie | CCSD

International audience. Proteins of the Chediak-Higashi/Beige (BEACH) family have been implicated in the function of lysosomes, as well as in signal transduction, but their molecular role is still poorly understood....

Identification of clathrin-adaptor medium chains in Dictyostelium discoideum : differential expression during development

Archive ouverte | de Chassey, Benoît | CCSD

International audience. Clathrin-adaptor complexes (APs) are vesicle coat components that participate in cargo selectivity;ind transport vesicle formation. Here we cloned and characterized apm1, apm3 and apm4 cDNAs ...

Ent3p Is a PtdIns(3,5)P2 effector required for protein sorting to the multivesicular body.

Archive ouverte | Friant, Sylvie | CCSD

PtdIns(3,5)P(2) is required for cargo-selective sorting to the vacuolar lumen via the multivesicular body (MVB). Here we show that Ent3p, a yeast epsin N-terminal homology (ENTH) domain-containing protein, is a specific PtdIns(3,5...

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