The fucosyltransferase gene family: An amazing summary of the underlying mechanisms of gene evolution.

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The fucosyltransferase gene family: An amazing summary of the underlying mechanisms of gene evolution.

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Javaud, C. | Dupuy, Fabrice | Maftah, Abderrahman | Julien, Raymond | Petit, Jean-Michel

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Langue: en

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The fucosyltransferase gene family: an amazing summary of the underlying mechanisms of gene evolution.

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α1,4-Fucosyltransferase Activity: A Significant Function in the Primate Lineage has Appeared Twice Independently

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International audience. In the animal kingdom the enzymes that catalyze the formation of alpha1,4 fucosylated-glycoconjugates are known only in apes (chimpanzee) and humans. They are encoded by FUT3 and FUT5 genes, ...

A single mutation confers an alpha-1,4 fucosylation ability to bovine fucosyltransferase fut4 but not to its human fut4 counterpart.

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