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Amphioxus functional genomics and the origins of vertebrate gene regulation

Archive ouverte | Marletaz, Ferdinand | CCSD

International audience. Vertebrates have greatly elaborated the basic chordate body plan and evolved highly distinctive genomes that have been sculpted by two whole-genome duplications. Here we sequence the genome o...

The retinoic acid signaling pathway regulates anterior/posterior patterning in the nerve cord and pharynx of amphioxus, a chordate lacking neural crest

Archive ouverte | Escriva, Hector | CCSD

Amphioxus, the closest living invertebrate relative of the vertebrates, has a notochord, segmental axial musculature, pharyngeal gill slits and dorsal hollow nerve cord, but lacks neural crest. In amphioxus, as in vertebrates, exo...

Evolution of retinoid and steroid signaling: vertebrate diversification from an amphioxus perspective

Archive ouverte | Albalat, Ricard | CCSD

International audience. Although the physiological relevance of retinoids and steroids in vertebrates is very well established, the origin and evolution of the genetic machineries implicated in their metabolic pathw...

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