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Joint modelling of repeated measurements and event time: Application to performance traits and survival of lambs bred in sub-humid tropics

Archive ouverte | Nguti, Rosemary | CCSD

International audience. We considered the analysis of a study for Dorper, Red Maasai and crossbred lambs born over a period of 6 years at the Diani Estate, Kenya. The study was designed to compare survival and perfo...

Validation of prognostic indices using the frailty model

Archive ouverte | Legrand, Catherine | CCSD

Chantier qualité GA. International audience. A major issue when proposing a new prognostic index is its generalisibility to daily clinical practice. Validation is therefore required. Most validation techniques asses...

Normalisation of brain spectroscopy findings in Niemann–Pick disease type C patients treated with miglustat

Archive ouverte | Sedel, Frédéric | CCSD

International audience. Niemann-Pick disease type C (NP-C) is a fatal progressive neurolipidosis involving neuronal storage of cholesterol and gangliosides. Miglustat, an inhibitor of glycosphingolipid synthesis, ha...

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