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GABAergic transmission underlies interictal epileptogenicity in pediatric FCD

Archive ouverte | Blauwblomme, Thomas | CCSD

International audience. Objective: Dysregulation of GABAergic transmission has been reported in lesional acquired epilepsies (gliomas, hippocampal sclerosis). We investigated its involvement ...

Pannexin-1 channels contribute to seizure generation in human epileptic brain tissue and in a mouse model of epilepsy

Archive ouverte | Dossi, Elena | CCSD

International audience

Chloride deregulation and GABA depolarization in MTOR-related malformations of cortical development

Archive ouverte | Bakouh, Naziha | CCSD

International audience. Abstract Focal cortical dysplasia, hemimegalencephaly and cortical tubers are paediatric epileptogenic malformations of cortical development (MCDs) frequently pharmacoresistant and mostly tre...

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