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A limited set of transcriptional programs define major cell types

Archive ouverte | Breschi, Alessandra | CCSD

International audience. We have produced RNA sequencing data for 53 primary cells from different locations in the human body. The clustering of these primary cells reveals that most cells in the human body share a f...

Gene-specific patterns of expression variation across organs and species

Archive ouverte | Breschi, Alessandra | CCSD

International audience. A comparison of transcriptional profiles derived from different tissues in a given species or among different species assumes that commonalities reflect evolutionarily conserved programs and ...

Enhanced transcriptome maps from multiple mouse tissues reveal evolutionary constraint in gene expression

Archive ouverte | Pervouchine, Dmitri | CCSD

International audience. Abstract Mice have been a long-standing model for human biology and disease. Here we characterize, by RNA sequencing, the transcriptional profiles of a large and heterogeneous collection of m...

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