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Rabenosyn-5, a Novel Rab5 Effector, Is Complexed with Hvps45 and Recruited to Endosomes through a Fyve Finger Domain

Archive ouverte | Nielsen, Erik | CCSD

International audience. Rab5 regulates endocytic membrane traffic by specifically recruiting cytosolic effector proteins to their site of action on early endosomal membranes. We have characterized a new Rab5 effecto...

APPL Proteins Link Rab5 to Nuclear Signal Transduction via an Endosomal Compartment

Archive ouverte | Miaczynska, Marta | CCSD

International audience. Signals generated in response to extracellular stimuli at the plasma membrane are transmitted through cytoplasmic transduction cascades to the nucleus. We report the identification of a pathw...

The Rab5 Effector Rabankyrin-5 Regulates and Coordinates Different Endocytic Mechanisms

Archive ouverte | Schnatwinkel, Carsten | CCSD

International audience

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