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Claudin-16 Deficiency Impairs Tight Junction Function in Ameloblasts, Leading to Abnormal Enamel Formation

Archive ouverte | Bardet, Claire | CCSD

International audience. Claudin-16 protein (CLDN16) is a component of tight junctions (TJ) with a restrictive distribution so far demonstrated mainly in the kidney. Here, we demonstrate the expression of CLDN16 also...

EMMPRIN/CD147 deficiency disturbs ameloblast–odontoblast cross-talk and delays enamel mineralization

Archive ouverte | Khaddam, Mayssam | CCSD

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Claudin Loss-of-Function Disrupts Tight Junctions and Impairs Amelogenesis

Archive ouverte | Bardet, Claire | CCSD

International audience. Claudins are a family of proteins that forms paracellular barriers and pores determining tight junctions (TJ) permeability. Claudin-16 and-19 are pore forming TJ proteins allowing calcium and...

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