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Active site mapping of yeast aspartyl-tRNA synthetase by in vivo selection of enzyme mutations lethal for cell growth

Archive ouverte | Ador, Laurent | CCSD

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Archive ouverte | Ador, Laurent | CCSD

Aminoacyl-tRNA synthetases contain one or three Mg(2+) ions in their catalytic sites. In addition to their role in ATP binding, these ions are presumed to play a role in catalysis by increasing the electropositivity of the alpha-p...

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Archive ouverte | Cavarelli, Jean | CCSD

International audience

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