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Metabolic rejuvenation upgrades circulatory functions of red blood cells stored in blood bank conditions Running head: Rejuvenation restores circulatory functions of stored RBC. Metabolic rejuvenation upgrades circulatory functions of red blood cells stored in blood bank conditions Running head: Rejuvenation restores circulatory functions of stored RBC: Rejuvenation restores circulatory functions of stored RBC

Archive ouverte | Marin, Mickaël | CCSD

International audience. BACKGROUNDRed blood cells (RBC) change upon hypothermic conservation, and storage for 6 weeks is associated with the short-term clearance of 15-20% of transfused RBC. Metabolic rejuvenation a...

Rapid clearance of storage-induced micro-erythrocytes alters transfusion recovery

Archive ouverte | Roussel, Camille | CCSD

International audience. Permanent availability of red blood cells (RBCs) for transfusion depends on refrigerated storage, during which morphologically altered RBCs accumulate. Among these, a subpopulation of small R...

Erythropoietin downregulates red blood cell clearance, increasing transfusion efficacy in severely anemic recipients

Archive ouverte | Casimir, Madeleine | CCSD

International audience. Red blood cells (RBC) transfusion is used to alleviate symptoms and prevent complications in anemic patients by restoring oxygen delivery to tissues. RBC transfusion efficacy, that can be mea...

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