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Bub3–BubR1-dependent sequestration of Cdc20Fizzy at DNA breaks facilitates the correct segregation of broken chromosomes

Archive ouverte | Derive, Nicolas | CCSD

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The Mre11-Rad50-Nbs1 complex mediates the robust recruitment of Polo to DNA lesions during mitosis in Drosophila

Archive ouverte | Landmann, Cedric | CCSD

International audience. The DNA damage sensor Mre11-Rad50-Nbs1 complex and Polo kinase are recruited to DNA lesions during mitosis. However, their mechanism of recruitment is elusive. Here, using live-cell imaging c...

Two RhoGEF isoforms with distinct localisation control furrow position during asymmetric cell division

Archive ouverte | Montembault, Emilie | CCSD

International audience. Cytokinesis partitions cellular content between daughter cells. It relies on the formation of an acto-myosin contractile ring, whose constriction induces the ingression of the cleavage furrow...

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