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Characterization of inflammatory osteoclasts : New therapeutic targets in chronic inflammatory diseases. Caractérisation des ostéoclastes inflammatoires : Nouvelles cibles thérapeutiques dans les maladies inflammatoires chroniques

Archive ouverte | Madel, Maria-Bernadette | CCSD

Osteoclasts (OCLs) are multinucleated cells responsible for physiological bone resorption and pathological bone destruction in osteoporosis and chronic inflammation. Recently, our team demonstrated that besides bone resorption, OC...

Dissecting the phenotypic and functional heterogeneity of mouse inflammatory osteoclasts by the expression of Cx3cr1

Archive ouverte | Madel, Maria-Bernadette | CCSD

International audience. Bone destruction relies on interactions between bone and immune cells. Boneresorbing osteoclasts (OCLs) were recently identified as innate immune cells activating T cells toward tolerance or ...

Porphyrin Derivatives Inhibit the Interaction between Receptor Activator of NF-κB and Its Ligand

Archive ouverte | Chypre, Melanie | CCSD

International audience

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