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Development of new strategies for formulation and functionalization of lipid nano-carriers for biomedical applications. Développement de nouvelles stratégies pour la formulation et la fonctionnalisation de nano-transporteurs lipidiques, destinés à des applications biomédicales

Archive ouverte | Rehman, Asad Ur | CCSD

The lipid nano-carriers are considered as mainstream delivery systems for lipophilic drugs because of their biocompatibility, high drug loading capacity and good biodistribution and pharmacokinetic profile. Nano-emulsions (NEs) co...

Spontaneous nano-emulsification with tailor-made amphiphilic polymers and related monomers

Archive ouverte | Rehman, Asad, Ur | CCSD

International audience. In general, nano-emulsions are submicron droplets composed of liquid oil phase dispersed in liquid aqueous bulk phase. They are stable and very powerful systems when it regards the encapsulat...

Compression of vectors for small interfering RNAs delivery: toward oral administration of siRNA lipoplexes in tablet form

Archive ouverte | Busignies, Virginie | CCSD

International audience. Currently, most nonviral nucleic acid vectors are in the form of colloidal suspensions administered primarily parenterally. This type of formulation and the mode of administration impose stro...

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