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Antagonistic effects of finerenone and spironolactone on the aldosterone‐regulated transcriptome of human kidney cells

Archive ouverte | Le Billan, Florian | CCSD

International audience. Aldosterone, the main mineralocorticoid hormone in humans, plays a pivotal role in the control of water and salt reabsorption via activation of the mineralocorticoid receptor (MR). Alteration...

Ulipristal Acetate Inhibits Progesterone Receptor Isoform A-Mediated Human Breast Cancer Proliferation and BCl2-L1 Expression

Archive ouverte | Esber, Nathalie | CCSD

International audience. The progesterone receptor (PR) with its isoforms and ligands are involved in breast tumori-genesis and prognosis. We aimed at analyzing the respective contribution of PR isoforms, PRA and PRB...

Behavior, Neural Structure, and Metabolism in Adult Male Mice Exposed to Environmentally Relevant Doses of Di(2-ethylhexyl) Phthalate Alone or in a Phthalate Mixture

Archive ouverte | Ducroq, Suzanne | CCSD

International audience. BACKGROUND: We have previously shown that chronic exposure of adult male mice to low doses of di(2-ethylhexyl) phthalate (DEHP) altered male sexual behavior and induced down-regulation of the...

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