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Expanding role for the apelin/APJ system in physiopathology.

Archive ouverte | Carpéné, C. | CCSD

International audience. Apelin is a bioactive peptide known as the ligand of the G protein-coupled receptor APJ. Diverse active apelin peptides exist under the form of 13, 17 or 36 amino acids, originated from a com...

The therapeutic potentials of apelin in obesity-associated diseases

Archive ouverte | Castan-Laurell, I. | CCSD

International audience. Apelin, a peptide with several active isoforms ranging from 36 to 12 amino acids and its receptor APJ, a G-protein-coupled receptor, are widely distributed. However, apelin has emerged as an ...

Healthy Aging Biomarkers: The INSPIRE's Contribution

Archive ouverte | Ader, Isabelle | CCSD

International audience. The find solutions for optimizing healthy aging and increase health span is one of the main challenges for our society. A novel healthcare model based on integration and a shift on research a...

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