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Electrochemical detection of the human cancer biomarker ‘autocrine motility factor-phosphoglucose isomerase’ based on a biosensor formed with a monosaccharidic inhibitor

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Ahmad, Lama | Salmon, Laurent | Korri-Youssoufi, Hafsa

Edité par CCSD ; Elsevier -

International audience. Human intracellular glycolytic enzyme phosphoglucose isomerase (hPGI) plays the role of autocrine motility factor (AMF) once secreted in the extracellular medium. AMF is a cytokine that stimulates tumor cell motility in vitro and metastases development in vivo. High blood levels of the protein have been reported to be closely related to metastases formation. Since it is

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