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Class I phosphoinositide 3-kinases control sustained NADPH oxidase activation in adherent neutrophils

Archive ouverte | Song, Zhimin | CCSD

Place: Oxford Publisher: Pergamon-Elsevier Science Ltd WOS:000551658300034. International audience. Phagocytes, especially neutrophils, can produce reactive oxygen species (ROS), through the activation of the NADPH ...

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Archive ouverte | Joly, Jérémy | CCSD

International audience. Neutrophils are the first cells recruited at the site of infections, where they phagocytose the pathogens. Inside the phagosome, pathogens are killed by proteolytic enzymes that are delivered...

Distinct timing of neutrophil spreading and stiffening during phagocytosis

Archive ouverte | Zak, Alexandra | CCSD

International audience. Phagocytic cells form the first line of defense in an organism, engulfing microbial pathogens. Phagocytosis involves cell mechanical changes that are not yet well understood. Understanding th...

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