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Design of the DREPAGREFFE trial: A prospective controlled multicenter study evaluating the benefit of genoidentical hematopoietic stem cell transplantation over chronic transfusion in sickle cell anemia children detected to be at risk of stroke by transcranial Doppler (NCT 01340404)

Archive ouverte | Chevret, Sylvie | CCSD

International audience. Background: Children with sickle cell anemia (SCA) have an 11% risk of stroke by the age of 18. Chronic transfusion applied in patients detected to be at risk by transcranial Doppler allows a...

Association of Matched-Sibling Donor Hematopoietic Stem Cell Transplantation with Transcranial-Doppler Velocities in Children with Sickle Cell Anemia

Archive ouverte | Bernaudin, Françoise | CCSD

International audience. Importance: In children with sickle cell anemia (SCA), high transcranial Doppler (TCD) velocities are associated with stroke risk, which is reduced by chronic transfusion. Whether matched sib...

Sickle cell disease: an international survey of results of HLA-identical sibling hematopoietic stem cell transplantation

Archive ouverte | Gluckman, Eliane | CCSD

International audience

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