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Practical identifiability in the frame of nonlinear mixed effects models: the example of the in vitro erythropoiesis

Archive ouverte | Duchesne, Ronan | CCSD

International audience. BackgroundNonlinear mixed effects models provide a way to mathematically describe experimental data involving a lot of inter-individual heterogeneity. In order to assess their practical ident...

Calibration, Selection and Identifiability Analysis of a Mathematical Model of the in vitro Erythropoiesis in Normal and Perturbed Contexts

Archive ouverte | Duchesne, Ronan | CCSD

International audience. The in vivo erythropoiesis, which is the generation of mature red blood cells in the bone marrowof whole organisms,has been described by a variety of mathematical models in the past decades. ...

Single-Cell-Based Analysis Highlights a Surge in Cell-to-Cell Molecular Variability Preceding Irreversible Commitment in a Differentiation Process

Archive ouverte | Richard, Angélique | CCSD

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