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A polygenic risk score for alcohol-associated cirrhosis among heavy drinkers with European ancestry

Archive ouverte | Schwantes-An, Tae-Hwi | CCSD

International audience. Background: Polygenic Risk Scores (PRS) based on results from genome-wide association studies offer the prospect of risk stratification for many common and complex diseases. We developed a PR...

Genome-wide association study and meta-analysis on alcohol-related liver cirrhosis identifies novel genetic risk factors

Archive ouverte | Schwantes-An, Tae-Hwi | CCSD

International audience. Background and aims - Only a minority of heavy drinkers progress to alcohol-associated cirrhosis (ALC). The aim of this study was to identify common genetic variants that underlie risk for AL...

Evaluation of laboratory tests for cirrhosis and for alcohol use, in the context of alcoholic cirrhosis

Archive ouverte | Whitfield, John B. | CCSD

International audience. Laboratory tests can play an important role in assessment of alcoholic patients, including for evaluation of liver damage and as markers of alcohol intake. Evidence on test performance should...

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