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An epitranscriptomic mechanism underlies selective mRNA translation remodelling in melanoma persister cells

Archive ouverte | Shen, Shensi | CCSD

International audience

An epitranscriptomic mechanism underlies selective mRNA translation remodelling in melanoma persister cells

Archive ouverte | Shen, Shensi | CCSD

International audience. Cancer persister cells tolerate anticancer drugs and serve as the founders of acquired resistance and cancer relapse. Here we show that a subpopulation of BRAFV600 mutant melanoma cells that ...

A PD-1/PD-L1 Proximity Assay as a Theranostic Marker for PD-1 Blockade in Patients with Metastatic Melanoma

Archive ouverte | Girault, Isabelle | CCSD

International audience. Abstract Purpose: Less than 50% of patients with melanoma respond to anti–programmed cell death protein 1 (anti–PD-1), and this treatment can induce severe toxicity. Predictive markers are th...

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