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Modification of Extracellular Vesicles by Fusion with Liposomes for the Design of Personalized Biogenic Drug Delivery Systems

Archive ouverte | Piffoux, Max | CCSD

International audience. Extracellular vesicles (EVs) are recognized as nature's own carriers to transport macromolecules throughout the body. Hijacking this endogenous communication system represents an attractive s...

Fluidic system for producing extracellular vesicles comprising a therapeutic or imaging agent and associated method. Système fluidique de production de vésicules extracellulaires comprenant un agent thérapeutique ou d’imagerie et procédé associé

Archive ouverte | Marangon, Iris | CCSD

The invention relates to a fluidic system for loading a therapeutic or imaging agent into the lumen of extracellular vesicles (EV) from producer cells, comprising at least one container, a liquid medium contained in the container,...

mTHPC-loaded extracellular vesicles significantly improve mTHPC diffusion and photodynamic activity in preclinical models

Archive ouverte | Millard, Marie | CCSD

International audience. Extracellular vesicles (EVs), derived from the cell, display a phospholipid bilayer membrane that protects the cargo molecules from degradation and contributes to increasing their stability i...

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