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Multiple serotonergic paths to antidepressant efficacy

Archive ouverte | Lutz, Pierre-Eric | CCSD

International audience. Lutz P.-E. Multiple serotonergic paths to antidepressant efficacy.Depression is a leading cause of disability worldwide. Brain mechanisms underlying the clinical anti-depressant efficacy of s...

Comorbidity between opiate addiction and depression : serotonergic mechanisms in a mouse model. La comorbidité entre dépendance aux opiacés et dépression : mécanismes sérotoninergiques dans un modèle murin

Archive ouverte | Lutz, Pierre-Eric | CCSD

Addiction is a chronic, frequent and serious brain disease, with relapse alternating with abstinence periods. Epidemiological studies show that abstinence, notably from opiates, is strongly associated with depression.Here we prese...

Childhood Maltreatment and Stress-Related Psychopathology: The Epigenetic Memory Hypothesis

Archive ouverte | Lutz, Pierre-Eric | CCSD

International audience. Childhood maltreatment (CM) is all too frequent among western societies, with an estimated prevalence of 10 to 15%. CM associates with increased risk of several psychiatric disorders, and the...

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