Long-Term Engraftment (16 Years) of Myoblasts in a Human Infarcted Heart

Archive ouverte

Crahes, Marie | Bories, Marie-Cécile | Vilquin, Jean-Thomas | Marolleau, Jean-Pierre | Desnos, Michel | Larghero, Jerome | Soulat, Gilles | Bruneval, Patrick | Hagège, Albert, A. | Menasché, Philippe

Edité par CCSD ; Wiley -

International audience. We report the case of a patient who had undergone injections of myoblasts in an infarct area 16 years before being referred for heart transplantation. The pathological examination of the explanted heart found persisting myotubes embedded in fibrosis. This finding supports the ability of myoblasts to survive in harsh environments, which can make them appealing candidates for transplantation in diseases requiring supply of new myogenic cells.

• Description
• Sujet/Public
• Outil
• Outil d'anticipation
• Mémoire et thèse
• Gestion