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Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility

Archive ouverte | Barc, Julien | CCSD

International audience. Brugada syndrome (BrS) is a cardiac arrhythmia disorder associated with sudden death in young adults. With the exception of SCN5A, encoding the cardiac sodium channel NaV1.5, susceptibility g...

Author Correction: Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility

Archive ouverte | Barc, Julien | CCSD

International audience

Heritability of aortic valve stenosis and bicuspid enrichment in families with aortic valve stenosis

Archive ouverte | Boureau, Anne-Sophie | CCSD

International audience. BACKGROUND: Although a familial component of calcific aortic valve stenosis (CAVS) has been described, its heritability remains unknown. Hence, we aim to assess the heritability of CAVS and t...

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