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The 2–5A/RNase L/RNase L Inhibitor (RNI) Pathway Regulates Mitochondrial mRNAs Stability in Interferon α-treated H9 Cells

Archive ouverte | Le Roy, Florence | CCSD

International audience

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Archive ouverte | Bisbal, Catherine | CCSD

International audience. The 2-5A/RNase L system is considered as a central pathway of interferon (IFN) action and could possibly play a more general physiological role as for instance in the regulation of RNA stabil...

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Archive ouverte | Martinand, Camille | CCSD

International audience. The interferon-regulated 2-5A/RNase L pathway plays a major role in the antiviral and antiproliferative activities of these cytokines. Several viruses, however, have evolved strategies to esc...

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