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Identification and functional expression of a second human β-galactoside α2,6-sialyltransferase, ST6Gal II

Archive ouverte | Krzewinski-Recchi, Marie-Ange | CCSD

International audience

Identification and functional expression of a second human beta-galactoside alpha2,6-sialyltransferase, ST6Gal II.

Archive ouverte | Krzewinski-Recchi, Marie-Ange | CCSD

International audience. BLAST analysis of the human and mouse genome sequence databases using the sequence of the human CMP-sialic acid:beta-galactoside alpha-2,6-sialyltransferase cDNA (hST6Gal I, EC2.4.99.1) as a ...

Probing the substrate specificity of four different sialyltransferases using synthetic beta-D-Galp-(1-->4)-beta-D-GlcpNAc-(1-->2)-alpha-D-Manp-(1-->O) (CH(2))7CH3 analogues general activating effect of replacing N-acetylglucosamine by N-propionylglucosamine.

Archive ouverte | F. Rohfritsch, Philippe | CCSD

The acceptor specificities of ST3Gal III, ST3Gal IV, ST6Gal I and ST6Gal II were investigated using a panel of beta-D-Galp-(1-->4)-beta-D-GlcpNAc-(1-->2)-alpha-D-Manp-(1-->O)(CH(2))(7)CH(3) analogues. Modifications introduced at e...

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